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How safe is the application of hyaluronic acid in the skin?

Hyaluron is a natural substance that occurs in our body. It is an important component of connective tissues such as synovial fluid, cartilage and the skin . Hyaluronic acid is a long-chain molecule that can bind water. This makes the skin plump and more elastic.

How is hyaluronic used?

In the cosmetics industry, hyaluronic acid is usually offered as a cream or serum. It can also be injected directly into the skin. As a result, it penetrates deeper into the skin layers and can work even more effectively. Hyaluron can also be used as a component of filler substances to add volume to the face or reduce wrinkles.

Is hyaluronic acid safe?

The application of hyaluronic acid in the skin is considered safe and unproblematic. However, there are certain side effects that can occur if used improperly:

  • redness
  • swelling
  • itching
  • Pains
  • inflammation

Another potential risk with hyaluron injections is the introduction of the substance into a vein. This can lead to occlusion of this vein. However, this is a risk inherent in any injection, regardless of the substance injected.

Who can use hyaluronic acid?

In Germany, it is regulated by law that hyaluronic acid injections may only be carried out by doctors. A cream or serum with hyaluronic acid can also be used by laypersons. However, the manufacturer's instructions should always be followed during use.

What does the European legislation say about hyaluronic acid?

According to the European Food Safety Authority, there is a permitted health claim for hyaluronic acid . This reads: " Hyaluronic acid helps maintain skin moisture and helps reduce wrinkles". This statement refers to the intake of hyaluronic acid as a dietary supplement, not to external use.


The application of hyaluronic acid in the skin is largely safe and harmless as long as it is carried out by trained personnel or in accordance with the manufacturer's instructions. However, as with any application of substances to the skin, there are potential risks to be aware of. Anyone who decides to use hyaluronic acid should always seek advice from an expert.

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